WHEN MEDICAL CONDITIONS MIMIC PSYCHIATRIC DISORDERS

June 22, 2026
Person in a green sweater holding a hand to their chest, showing a close-up of discomfort.

Many people are surprised to learn that symptoms such as anxiety, depression, difficulty concentrating, irritability, insomnia, memory problems, and even panic attacks may not always be caused solely by a psychiatric condition.


As a physician and psychiatrist, one of my most important responsibilities is to consider whether an underlying medical condition may be contributing to emotional, behavioral, or cognitive symptoms.


A comprehensive psychiatric evaluation involves much more than assigning a diagnosis. It requires understanding the whole person, including their medical history, medications, family history, lifestyle, sleep patterns, nutrition, and any physical symptoms that may be present.


Numerous medical conditions can produce symptoms that resemble psychiatric disorders. Examples include:


  • Thyroid disorders, which can contribute to anxiety, depression, irritability, fatigue, or difficulty concentrating
  • Hormonal changes, including menopause, perimenopause, and other endocrine disorders that may affect mood, sleep, and emotional regulation
  • Vitamin deficiencies, such as low levels of Vitamin B12, folate, or Vitamin D, which may contribute to fatigue, low mood, memory difficulties, and cognitive changes
  • Sleep disorders, including sleep apnea, which can result in depression, anxiety, irritability, poor concentration, and daytime fatigue
  • Autoimmune and inflammatory conditions, which may affect mood, cognition, and overall functioning
  • Neurological disorders, including seizure disorders, head injuries, and certain neurodegenerative conditions that can present with emotional or behavioral symptoms
  • Medication side effects, which may sometimes contribute to anxiety, depression, agitation, insomnia, or cognitive difficulties


While medical factors do not explain every psychiatric symptom, overlooking them can lead to incomplete treatment and unnecessary suffering.


My approach is to integrate medical, psychological, developmental, family, and social factors in order to develop a comprehensive understanding of each patient. In some cases, laboratory testing, review of medical records, collaboration with other physicians, or additional diagnostic evaluation may be appropriate.


Psychiatric symptoms are real and deserve careful attention. At the same time, it is important to recognize that emotional and behavioral symptoms can sometimes be the first sign of an underlying medical condition.


A thoughtful evaluation helps ensure that treatment recommendations address not only the symptoms themselves, but also any contributing medical factors that may be affecting overall well-being.


Physician-Led Psychiatry for the Whole Person